I have a suspicion that something hardware related can affect the playability of bonelab. On my setup I had no problem outrunning the train, friend of mine has been frothing at the mouth complaining he can't do it, there just isn't enough time. I go over to his place and say i'll do it for him and what do I find? You can't get anywhere NEAR the second platform before the train smacks you, yes that's with the FAST frame.
I got home, hopped on mine, went back to that level and nailed it first try with time to spare.