>>352592094
Downloading 60+ mods without testing is a bad idea in the first place but you can get away with it if you pick carefully and sort them well in Mod Organizer. If you want to build an even larger and stable modded Skyrim you should test as you go and install the gameplay mods last. 
>Core VR mods + alternative start of choice
>Terrain/Tree/LOD replacers
>Vegetation, water and weather
>Then finally your major gameplay overhauls
Misc textures and small mods rarely need testing so just thrown them in at the end. Testing each step lets you see if you like the options chosen for each mod and whether you can afford to lower the texture detail, do you really need 4k textures on underwater sand? If you use Cathedral mods for most of these it's trivial, the only parts that will need a tutorial for your first time are the LOD replacing and doing a Bash patch right at the end.