>>289181065
Disable everything else but Avatar and Voice, leave those on.
You don't need to see everyone's shaders, it's not like they're setup to be nice looking and pretty. Most people who have custom shaders look the same as if they were using Unlit.

You should also disable everything for anyone who is not your friend, except for their voice and selectively enable avatars for people you're talking to.

Why? Because VRChat does not unload people's avatars from memory, and the larger the filesize of the avatar, the worse your performance gets overtime.

I suggest restarting once in a while as well.

tl;dr hide everything but people's Avatar (don't mute them), only show friends Avatars and selectively fully enable avatars close to you that you're talking to.
Also use the dynamic bone limiter in advanced settings.